SCHEMBL10696976

SCHEMBL10696976

Cc1c(C(=O)c2ncccc2C(=O)O)c2ccccc2n1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MAPT P10636 3/20 0.49
KDM4E B2RXH2 3/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
BLM P54132 1/20 0.49
AGER Q15109 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MYC P01106 3/20 0.48
EGFR P00533 4/20 0.45
KMT2A Q03164 4/20 0.44
SRC P12931 4/20 0.44
MEN1 O00255 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815397 0.85 EGFR (0.48) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL6131241 0.84 CNR2 (0.48) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL11250963 0.82 EGFR (0.56) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL10658054 0.82 CNR2 (0.47) ALDH1A1MAPTTSHRKMT2AMEN1
SCHEMBL8862307 0.82 CNR2 (0.63) CNR1CNR2
SCHEMBL8862272 0.81 KDM4E (0.46) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL8862273 0.81 CNR2 (0.64) CNR1CNR2
SCHEMBL14398407 0.79 KMT2A (0.46) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL984736 0.77 EGFR (0.65) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL30443220 0.77 EGFR (0.65) ALDH1A1MAPTKDM4ENPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0265954-A2 Light-sensitive material containing silver halide, reducing agent and polymerizable compound Fuji Photo Film Co., Ltd. (JP) 1988-05-04 EP disclosed