Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698203 | 0.82 | PPARD (0.39) | PPARDLPAR2LPAR3 | |
| SCHEMBL646400 | 0.81 | CETP (0.49) | LPAR2LPAR3TSHRCETP | |
| SCHEMBL28985843 | 0.79 | CETP (0.51) | LPAR2LPAR3TSHRCETP | |
| SCHEMBL27809982 | 0.77 | LPAR2 (0.35) | PPARDLPAR2LPAR3 | |
| SCHEMBL22639044 | 0.74 | PPARD (0.36) | PPARDLPAR2LPAR3TSHR | |
| SCHEMBL5136434 | 0.74 | LPAR3 (0.43) | LPAR2LPAR3 | |
| SCHEMBL3278680 | 0.74 | TSHR (0.46) | LPAR2LPAR3PKMSMN1; SMN2TSHR | |
| SCHEMBL436759 | 0.74 | LPAR2 (0.36) | LPAR2LPAR3 | |
| SCHEMBL4410387 | 0.74 | — | — | |
| SCHEMBL11667403 | 0.73 | MEN1 (0.41) | LPAR2LPAR3PKMSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271170-A2 | Herbicidal substituted benzofurans and benzopyrans | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | disclosed |
| EP-0254774-A1 | Method for controlling phosphonates tending to precipitate metal ions in water | DENAC N.V. (BE) | 1988-02-03 | — | — | EP | disclosed |