Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 2/20 | 0.45 |
| ▸ | F3 | P13726 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10697760 | 0.87 | ASAH2 (0.44) | ASAH2MAPTBLMGMNNUSP2 | |
| SCHEMBL10697469 | 0.85 | ASAH2 (0.42) | ASAH2MAPTBLMGMNNUSP2 | |
| SCHEMBL10697463 | 0.85 | ASAH2 (0.42) | ASAH2MAPTBLMGMNNUSP2 | |
| Acetic Acid SCHEMBL10698331 | 0.79 | MAPT (0.57) | ASAH2MAPTBLMGMNNLMNA | |
| SCHEMBL17350089 | 0.77 | PPARG (0.34) | ASAH2PPARGPPARDPPARAMAPT | |
| SCHEMBL17350090 | 0.77 | PPARG (0.34) | ASAH2PPARGPPARDPPARAMAPT | |
| Hydrochloric Acid SCHEMBL11767811 | 0.76 | SPHK2 (0.58) | ASAH2MAPTBLMGMNNLMNA | |
| SCHEMBL10699279 | 0.76 | SPHK2 (0.62) | ASAH2MAPTBLMGMNNLMNA | |
| SCHEMBL10699276 | 0.76 | SPHK2 (0.62) | ASAH2MAPTBLMGMNNLMNA | |
| SCHEMBL17703964 | 0.76 | SPHK2 (0.62) | ASAH2MAPTBLMGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283946-A1 | Novel intermediates useful in preparing vitamin E | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-28 | — | — | EP | disclosed |