Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11730503 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9250794 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL30457827 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9065873 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL15799393 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL17225127 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL2127368 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4436496 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL16598580 | 0.95 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL29127648 | 0.95 | CA1 (0.50) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452522-A | A kind of effectively insulating insulating sponge | WUXI JING SHANG FOAM CO LTD | 2019-11-15 | — | — | CN | claimed |
| CN-110316968-A | It is a kind of to burn polymorphic multicolour crystalline glaze and its preparation method and application fastly | 江西陶瓷工艺美术职业技术学院 | 2019-10-11 | — | — | CN | claimed |
| CN-106566071-B | Modified polypropylene composite material and preparation method thereof | 广西师范学院 | 2019-07-26 | — | — | CN | claimed |
| CN-109400971-A | A kind of elastic preferably pet tennis and preparation method thereof | 天长市富宝橡塑制品有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-104975297-B | Bio-based calcium and magnesium sedimentary and forming method thereof assembles bait and the rich material of calcium and magnesium with special marine growth | 中海油能源发展股份有限公司 | 2017-06-20 | — | — | CN | claimed |
| CN-106566071-A | Modified polypropylene composite material and preparation method thereof | 广西师范学院 | 2017-04-19 | — | — | CN | claimed |
| CN-106345803-A | Soil disinfection and soil restoration method | 湖南科技学院 | 2017-01-25 | — | — | CN | claimed |
| CN-106349584-A | Fiber-reinforced composite building board and preparation method thereof | 赵碧华 | 2017-01-25 | — | — | CN | claimed |
| CN-106277982-A | A kind of Concha Tridacna squamosa mud of energy the nerves calming and preparation method thereof | 成都斯米利亚硅藻新材料有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-106279812-A | A kind of slush pump piston cup and preparation method thereof | 天津碧宇舟机械制造有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-106077577-A | A kind of low-pressure casting mould for wheel hub | 盛跃丹 | 2016-11-09 | — | — | CN | claimed |
| CN-102784275-B | Tongzhisurunjiang tablet for activating retardation and softening and preparation and quality control method thereof | WUHAN JIANHENG PHARMACEUTICAL CO LTD | 2014-02-26 | — | — | CN | claimed |
| CN-102784275-A | Tongzhisurunjiang tablet for activating retardation and softening and preparation and quality control method thereof | WUHAN JIANHENG PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | claimed |
| EP-0286601-A2 | Powdered deodorant composition for shoes, in particular for sporting shoes | Campodonico, Bruno (IT) | 1988-10-12 | — | — | EP | claimed |
| CN-110316968-A | It is a kind of to burn polymorphic multicolour crystalline glaze and its preparation method and application fastly | 江西陶瓷工艺美术职业技术学院 | 2019-10-11 | — | — | CN | disclosed |
| CN-106566071-B | Modified polypropylene composite material and preparation method thereof | 广西师范学院 | 2019-07-26 | — | — | CN | disclosed |
| CN-106566071-B | Modified polypropylene composite material and preparation method thereof | 广西师范学院 | 2019-07-26 | — | — | CN | disclosed |
| CN-100400743-C | Quick cold soaking and mechanical pulping process for grass family | DONGYING ZHONGSHENG ENVIRONMEN (CN) | 2008-07-09 | — | — | CN | disclosed |
| CN-1800487-A | Quick cold soaking and mechanical pulping process for grass family | DONGYING ZHONGSHENG ENVIRONMEN (CN) | 2006-07-12 | — | — | CN | disclosed |
| EP-0286601-A2 | Powdered deodorant composition for shoes, in particular for sporting shoes | Campodonico, Bruno (IT) | 1988-10-12 | — | — | EP | disclosed |