Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 13/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697672 | 1.00 | GRIN1 (0.50) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL10697667 | 1.00 | GRIN1 (0.50) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19253322 | 0.86 | GRIN1 (0.67) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19253320 | 0.86 | GRIN1 (0.67) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL8134278 | 0.82 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL17697479 | 0.82 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL16407519 | 0.82 | GRIN1 (0.49) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19733248 | 0.82 | GRIN1 (0.69) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19253216 | 0.82 | GRIN1 (0.69) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2435125 | 0.81 | MAPK1 (0.74) | GRIN1GRIN2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288102-A1 | Novel 2 beta, 16beta-diamino-androstanes | AKZO N.V. (NL) | 1988-10-26 | — | — | EP | disclosed |