⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696378 | 0.83 | — | — | |
| SCHEMBL23444954 | 0.72 | — | — | |
| SCHEMBL14649565 | 0.69 | — | — | |
| SCHEMBL1106718 | 0.69 | — | — | |
| SCHEMBL265331 | 0.69 | — | — | |
| SCHEMBL25140652 | 0.69 | — | — | |
| SCHEMBL37255 | 0.69 | — | — | |
| SCHEMBL25140651 | 0.69 | — | — | |
| SCHEMBL5306053 | 0.69 | CA1 (1.00) | — | |
| SCHEMBL265674 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166625-A1 | Substituted 4-Benzyl And 4-Benzoyl Piperidine Derivates | CEPHALON LLC | 2024-05-23 | — | — | US | disclosed |
| US-20240166661-A1 | Spiropiperidine Derivatives | CEPHALON LLC | 2024-05-23 | — | — | US | disclosed |
| US-11878982-B2 | Spiropiperidine derivatives | 89BIO LTD (IL) | 2024-01-23 | — | — | US | disclosed |
| US-11878966-B2 | Substituted 4-benzyl and 4-benzoyl piperidine derivates | 89BIO LTD (IL) | 2024-01-23 | — | — | US | disclosed |
| US-20230391723-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2023-12-07 | — | — | US | disclosed |
| US-11702388-B2 | 1,4-substituted piperidine derivatives | 89BIO LTD (IL) | 2023-07-18 | — | — | US | disclosed |
| US-20210284651-A1 | Spiropiperidine Derivatives | CEPHALON LLC | 2021-09-16 | — | — | US | disclosed |
| US-20210230116-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2021-07-29 | — | — | US | disclosed |
| US-11046707-B2 | Spiropiperidine derivatives | 89BIO LTD (IL) | 2021-06-29 | — | — | US | disclosed |
| CN-107847765-B | 1, 4-substituted piperidine derivatives | 89生物有限公司 | 2021-05-04 | — | — | CN | disclosed |
| US-9902696-B2 | 1,4-substituted piperidine derivatives | CEPHALON, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-9670335-B2 | Compositions containing tetrahydrofurfuryl and/or alkyl-substituted tetrahydrofurfuryl esters of citric acid | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-06 | — | — | US | disclosed |
| WO-2016205633-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-12-22 | — | — | WO | disclosed |
| US-20160368874-A1 | 1,4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON LLC | 2016-12-22 | — | — | US | disclosed |
| WO-2016205590-A1 | SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-12-22 | — | — | WO | disclosed |
| US-20150033985-A1 | COMPOSITIONS CONTAINING TETRAHYDROFURFURYL AND/OR ALKYL-SUBSTITUTED TETRAHYDROFURFURYL ESTERS OF CITRIC ACID | 3M INNOVATIVE PROPERTIES COMPANY | 2015-02-05 | — | — | US | disclosed |
| EP-2831065-A1 | COMPOSITIONS CONTAINING TETRAHYDROFURFURYL AND/OR ALKYL-SUBSTITUTED TETRAHYDROFURFURYL ESTERS OF CITRIC ACID | 3M Innovative Properties Company (US) | 2015-02-04 | — | — | EP | disclosed |
| CN-104271570-A | Composition comprising tetrahydrofurfuryl and/or alkyl-substituted tetrahydrofurfuryl esters of citric acid | 3M INNOVATIVE PROPERTIES CO | 2015-01-07 | — | — | CN | disclosed |
| WO-2013148255-A1 | COMPOSITIONS CONTAINING TETRAHYDROFURFURYL AND/OR ALKYL-SUBSTITUTED TETRAHYDROFURFURYL ESTERS OF CITRIC ACID | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-03 | — | — | WO | disclosed |
| EP-0253767-A1 | Parasiticide and insecticide | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |