Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583189 | 0.93 | TSHR (0.46) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL105694 | 0.92 | TSHR (0.55) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL19583216 | 0.90 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL11581248 | 0.89 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL19583187 | 0.86 | TSHR (0.49) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL4957917 | 0.86 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL28348648 | 0.86 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL11803433 | 0.85 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL2921941 | 0.85 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL752302 | 0.84 | TSHR (0.53) | TSHRHPGDTHRBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280295-A2 | A heat-resistant photosensitive resin composition | TOKYO OHKA KOGYO CO., LTD. (JP) | 1988-08-31 | — | — | EP | disclosed |