Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18436103 | 1.00 | TSHR (0.58) | TSHRMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL16215117 | 1.00 | TSHR (0.58) | TSHRMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL30885138 | 0.84 | MAPT (0.60) | TSHRMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL7790503 | 0.81 | MAPT (0.57) | TSHRMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL18436831 | 0.81 | MAPT (0.57) | TSHRMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL23731989 | 0.81 | MAPT (0.57) | TSHRMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL24352865 | 0.81 | MAPT (0.57) | TSHRMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL327800 | 0.81 | MAPT (0.57) | TSHRMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL19139371 | 0.79 | BPTF (0.54) | MAPTALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL26496330 | 0.79 | BPTF (0.54) | MAPTALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |
| EP-2445887-B1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD (IN) | 2014-11-05 | — | — | EP | disclosed |
| US-7244486-B2 | Optical recording medium and optical recording method | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-07-17 | — | — | US | disclosed |
| US-7244486-B2 | Optical recording medium and optical recording method | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-0262307-A2 | Process for preparing hydroxymorpholines and morpholines | TEXACO DEVELOPMENT CORPORATION (US) | 1988-04-06 | — | — | EP | disclosed |
| US-4670557-A | Process for preparing hydroxymorpholines | TEXACO INC. (US) | 1987-06-02 | — | — | US | disclosed |
| US-4085160-A | VINYL ESTER RESIN, N-PHENYLMORPHOLINE | THE DOW CHEMICAL COMPANY (US) | 1978-04-18 | — | — | US | disclosed |