SCHEMBL10698474

SCHEMBL10698474

CNC1CCCCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23595739 1.00
SCHEMBL18239349 1.00
SCHEMBL12309751 0.98 KMT2A (0.52)
SCHEMBL13044935 0.98 KMT2A (0.52)
Hydrochloric Acid SCHEMBL10965326 0.98 CA1 (0.48)
Benzene SCHEMBL29051407 0.94 CA1 (0.45)
SCHEMBL19695675 0.93
Chlorobenzene SCHEMBL28579335 0.82 MAPT (0.47)
Fluorobenzene SCHEMBL28699414 0.82 MCL1 (0.41)
SCHEMBL28282310 0.76 CA1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200253894-A1 INTRANASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 2020-08-13 US claimed
US-4051308-A Process for polymerizing butadiene with cobalt complex, AlR3 and CS2 THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-09-27 US claimed
WO-2025111597-A1 A TREATMENT FOR PATIENTS WITH MOOD DISORDERS USING N-ETHYL-2-(5-FLUORO-1H-INDOL-3-YL)- N-METHYLETHAN-1-AMINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF GILGAMESH PHARMACEUTICALS, INC. (US) 2025-05-30 WO disclosed
US-20240415848-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-12-19 US disclosed
EP-4337182-A1 REDUCING SIDE EFFECTS OF NMDA RECEPTOR ANTAGONISTS Seelos Therapeutics, Inc. (US) 2024-03-20 EP disclosed
CN-116942646-A R-ketamine liquid preparation and application thereof 宜昌人福药业有限责任公司 2023-10-27 CN disclosed
WO-2023133554-A2 MICROSPHERE FORMULATIONS COMPRISING KETAMINE AND METHODS FOR MAKING AND USING THE SAME OAKWOOD LABORATORIES, LLC (US) 2023-07-13 WO disclosed
WO-2022241315-A1 REDUCING SIDE EFFECTS OF NMDA RECEPTOR ANTAGONISTS SEELOS THERAPEUTICS, INC. (US) 2022-11-17 WO disclosed
EP-3908571-A1 KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF XWPharma Ltd. (KY) 2021-11-17 EP disclosed
WO-2021134086-A1 ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2021-07-01 WO disclosed
WO-2021121366-A1 LONG-ACTING INJECTABLE FORMULATIONS OF KETAMINE PAMOATE SALTS ALAR PHARMACEUTICALS INC. (CN) 2021-06-24 WO disclosed
US-7314936-B2 Deazapurines and uses thereof EISAI CO., LTD. (JP) 2008-01-01 US disclosed
US-7314936-B2 Deazapurines and uses thereof EISAI CO., LTD. (JP) 2008-01-01 US disclosed
WO-2007117180-A1 AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) 2007-10-18 WO disclosed
EP-0254313-A2 Use of ketamine for the manufacturing of medicaments for prevention or reduction of the effects of stroke in a subject having increased risk for stroke WARNER-LAMBERT COMPANY (US) 1988-01-27 EP disclosed
US-4258160-A BY USE OF A CATALYST COMPRISING A COBALT-CONTAINING COMPONENT, AN ALKYL ALUMINUM COMPONENT, AND CARBONYL SULFIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-03-24 US disclosed
US-4248988-A CATALYST SYSTEM COMPRISING COBALT OR NICKEL COMPONENT, HYDROCARBYL ALUMINUM, AND HALOGENATED HYDROCARBON THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-02-03 US disclosed
US-4198496-A COBALT COMPONENT, MAGNESIUM OR MANGANESE CHLORIDE, IODIDE OR CARBOXYLIC ACID SATL, ORGANOALUMINUM HALIDE AS CATALYST THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-04-15 US disclosed
US-4051308-A Process for polymerizing butadiene with cobalt complex, AlR3 and CS2 THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-09-27 US disclosed
US-3993856-A CATALYST OF COBALT COMPOUND, HYDRO- OR HYDROCARBYLALUMINUM DIHALIDE, AND CARBON DISULFIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-11-23 US disclosed