SCHEMBL10698879

SCHEMBL10698879

O=P(O)(O)OCCCC(S)S

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.48
LPAR2 Q9HBW0 6/20 0.48
LPAR1 Q92633 4/20 0.48
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
SMPD1 P17405 3/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
LPAR5 Q9H1C0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1923637 0.77 LPAR3 (0.54) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL1574125 0.77 LPAR3 (0.71) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL1576717 0.77 LPAR3 (0.64) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL11237298 0.76 LPAR3 (0.47) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL9233772 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL28124639 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL27042238 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL27042244 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL6033633 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL6851142 0.75 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259974-A2 Overbased sulfurized alkyl-phenols as lubricating oil additives CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-03-16 EP disclosed