Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764117 | 0.86 | KDM4E (0.47) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL10433439 | 0.85 | GAA (0.47) | KDM4ETDP1ALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL10765883 | 0.85 | KDM4E (0.46) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL6831687 | 0.83 | HRH4 (0.41) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL8699829 | 0.81 | ESR1 (0.46) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL10572503 | 0.78 | KDM4E (0.57) | KDM4ETDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL10514956 | 0.76 | HTR2C (0.48) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL6626014 | 0.74 | KDM4E (0.38) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL7214494 | 0.74 | KDM4E (0.43) | KDM4ETDP1ALDH1A1HPGDGAA | |
| SCHEMBL6280799 | 0.71 | KDM4E (0.59) | KDM4ETDP1ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |