Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562352 | 0.94 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL12637996 | 0.93 | KDM4E (0.94) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10561493 | 0.93 | KDM4E (0.82) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10563510 | 0.92 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10563935 | 0.92 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9534556 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Marbofloxacin SCHEMBL134860 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Marbofloxacin SCHEMBL29355042 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10557702 | 0.90 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Marbofloxacin SCHEMBL10563057 | 0.89 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259804-A2 | Pyrido[3,2,1-ij]-1,3,4-benzoxadiazine derivatives, process for their preparation, resulting pharmaceutical preparations and intermediates for use in the process | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-16 | — | — | EP | claimed |