SCHEMBL10700367

SCHEMBL10700367

CC(c1ccccc1)c1ccc(C#N)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
OPRD1 P41143 2/20 0.50
MAOB P27338 3/20 0.47
MAOA P21397 2/20 0.47
CYP19A1 P11511 5/20 0.46
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 1/20 0.44
F2R P25116 1/20 0.41
ALOX5AP P20292 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
TRPA1 O75762 1/20 0.40
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA6 P23280 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17071852 1.00 TSHR (0.54) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL17071848 1.00 TSHR (0.54) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL22841886 0.94 TSHR (0.48) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL22842130 0.94 TSHR (0.48) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL7799578 0.91 CYP2A6 (0.52) TSHRCYP19A1CYP2A6ALDH1A1CA12
SCHEMBL30509594 0.87 TSHR (0.54) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL22841999 0.83 IRAK4 (0.41) TSHROPRD1MAOBCYP19A1
SCHEMBL12229906 0.83 CYP2A6 (0.70) TSHRCYP19A1CYP2A6ALDH1A1CA12
SCHEMBL29038977 0.82 CYP19A1 (0.63) TSHROPRD1MAOBMAOACYP19A1
SCHEMBL1343704 0.82 CYP19A1 (0.63) TSHROPRD1MAOBMAOACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118251445-A Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same 信越化学工业株式会社 2024-06-25 CN disclosed
CN-112236464-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2024-02-23 CN disclosed
CN-112204076-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-116813824-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
CN-113646393-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2023-09-19 CN disclosed
CN-116490350-A Resin composition, prepreg, resin sheet, metal foil-clad laminate, and printed wiring board 三菱瓦斯化学株式会社 2023-07-25 CN disclosed
CN-116490555-A Copper-clad laminate and printed circuit board 三菱瓦斯化学株式会社 2023-07-25 CN disclosed
CN-116438244-A Crosslinkable organosiloxane modified reactive resins 瓦克化学股份公司 2023-07-14 CN disclosed
CN-113348079-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2023-06-02 CN disclosed
EP-3483227-B1 COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME SWIMC LLC (US) 2020-12-16 EP disclosed
EP-3483227-A1 COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME Swimc, LLC (US) 2019-05-15 EP disclosed
EP-0263022-A1 Mesomorphic polymers containing side chains, derived from 1-(phenyl)-2-(4-cyanophenyl) ethane THOMSON-CSF (FR) 1988-04-06 EP disclosed