Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979348 | 1.00 | CALCRL (0.38) | CALCRLPTGDR2 | |
| SCHEMBL979347 | 1.00 | CALCRL (0.38) | CALCRLPTGDR2 | |
| SCHEMBL979128 | 1.00 | CALCRL (0.38) | CALCRLPTGDR2 | |
| SCHEMBL979126 | 1.00 | CALCRL (0.38) | CALCRLPTGDR2 | |
| SCHEMBL979129 | 1.00 | CALCRL (0.38) | CALCRLPTGDR2 | |
| SCHEMBL976466 | 0.89 | CALCRL (0.37) | CALCRLPTGDR2 | |
| SCHEMBL976469 | 0.89 | CALCRL (0.37) | CALCRLPTGDR2 | |
| SCHEMBL980013 | 0.81 | CALCRL (0.35) | CALCRL | |
| SCHEMBL980014 | 0.81 | CALCRL (0.35) | CALCRL | |
| SCHEMBL980015 | 0.81 | CALCRL (0.35) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271346-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009120652-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-10-01 | — | — | WO | disclosed |