Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.46 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18214509 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Hydrogen Sulfide SCHEMBL11010306 | 0.97 | GGPS1 (0.44) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL11687981 | 0.97 | GGPS1 (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL15613358 | 0.97 | — | — | |
| SCHEMBL13767876 | 0.88 | — | — | |
| SCHEMBL10704293 | 0.80 | GGPS1 (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16970194 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16970061 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16969681 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16970324 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252736-A2 | Process for preparing fluorine-containing carboxylic acid ester | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-01-13 | — | — | EP | disclosed |