SCHEMBL1070323

SCHEMBL1070323

O=S(=O)(O)c1cccc(Br)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.45
CA1 P00915 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
TTR P02766 2/20 0.42
PLCG1 P19174 1/20 0.42
CYP1A2 P05177 2/20 0.40
CDK2 P24941 2/20 0.39
ACHE P22303 1/20 0.38
PGAM1 P18669 1/20 0.37
AURKA O14965 1/20 0.37
AURKB Q96GD4 1/20 0.37
MYC P01106 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NSD2 O96028 1/20 0.36
POLB P06746 1/20 0.36
PKM P14618 1/20 0.36
BLM P54132 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446869 0.84 TTR (0.50) TTRCYP1A2CDK2PGAM1AURKA
SCHEMBL7784949 0.81 TTR (0.48) TTRCYP1A2CDK2PGAM1AURKA
SCHEMBL28244623 0.80 CA1 (0.46) CA2CA1CA4CA6TTR
SCHEMBL29412674 0.80 CA1 (0.46) CA2CA1CA4CA6TTR
SCHEMBL10638256 0.80 CA1 (0.46) CA2CA1CA4CA6TTR
SCHEMBL122413 0.79 CA1 (0.62) CA2CA1CA4CA6TTR
SCHEMBL30873490 0.79 CA1 (0.62) CA2CA1CA4CA6TTR
Hydrochloric Acid SCHEMBL27627273 0.78 CA1 (0.45) CA2CA1CA4CA6TTR
SCHEMBL6913327 0.77 CA1 (0.60) CA2CA1CA4CA6TTR
SCHEMBL6916922 0.77 CA1 (0.60) CA2CA1CA4CA6TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387391-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2011-11-23 EP disclosed
WO-2011009436-A9 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-03-31 WO disclosed
WO-2011009436-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-01-27 WO disclosed
US-4931549-A Process for aryl-quinone and aryl-naphthoquinone diazide sulfonic acids HOECHST CELANESE CORPORATION (US) 1990-06-05 US disclosed
EP-0283898-A2 Preparation process of aryldiazidsulfonic acids HOECHST CELANESE CORPORATION (US) 1988-09-28 EP disclosed