Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.46 |
| ▸ | KDM5A | P29375 | 7/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746083 | 0.93 | EPHX2 (0.55) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL8354604 | 0.90 | KDM4C (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL1832887 | 0.88 | EPHX2 (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL1837811 | 0.88 | EPHX2 (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL1834688 | 0.88 | EPHX2 (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL23732848 | 0.88 | EPHX2 (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL1830915 | 0.88 | EPHX2 (0.53) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL19316250 | 0.86 | KDM4C (0.44) | EPHX2EPHX1KDM4CKDM5APHF8 | |
| SCHEMBL1831077 | 0.86 | EPHX2 (0.50) | EPHX2KDM4CKDM5APHF8KDM4A | |
| SCHEMBL2482309 | 0.85 | EPHX2 (0.70) | EPHX2KDM4CKDM5APHF8KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138504-B1 | STEROID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-20 | — | — | EP | disclosed |
| US-4659516-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0138504-A2 | Steroid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-04-24 | — | — | EP | disclosed |