Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.69 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | GGT1 | P19440 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988737 | 0.88 | HSD17B10 (0.71) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL789771 | 0.88 | HSD17B10 (0.71) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL29669847 | 0.88 | HSD17B10 (0.71) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL1162463 | 0.86 | KDM4E (0.69) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL14972 | 0.86 | HSD17B10 (0.69) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL30941613 | 0.86 | KDM4E (0.69) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL11521148 | 0.85 | KDM4E (0.73) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL15721292 | 0.85 | HSD17B10 (0.67) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL9263640 | 0.85 | HSD17B10 (0.67) | HSD17B10KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL9228274 | 0.85 | HSD17B10 (0.67) | HSD17B10KDM4ELMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108821-B1 | COMPOSITIONS FOR TREATING ACNE | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-01-07 | — | — | EP | claimed |
| EP-3983369-A1 | PROCESS FOR THE PRODUCTION OF DIACYL PEROXIDES | Nouryon Chemicals International B.V. (NL) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249690-A1 | PROCESS FOR THE PRODUCTION OF DIACYL PEROXIDES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-12-17 | — | — | WO | disclosed |