Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.70 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | OSBP | P22059 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177708 | 1.00 | POLA1 (0.70) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL7787254 | 1.00 | POLA1 (0.70) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL7787257 | 1.00 | POLA1 (0.70) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL29055425 | 1.00 | POLA1 (0.70) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL24437941 | 0.93 | POLA1 (0.66) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL25990906 | 0.93 | POLA1 (0.66) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL25249402 | 0.93 | POLA1 (0.66) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL25249401 | 0.93 | POLA1 (0.66) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL23070074 | 0.92 | POLA1 (0.72) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL10936315 | 0.92 | POLA1 (0.72) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127829-B1 | IMPROVED STEROID ESTERS PREPARATION | AB LEO (SE) | 1988-02-24 | — | — | EP | disclosed |
| US-4537722-A | CARBODIIMIDES WITH ACID CATALYSTS ARE USED AS CONDENSING AGENTS | AB LEO (SE) | 1985-08-27 | — | — | US | disclosed |
| EP-0127829-A2 | Improved steroid esters preparation | AB LEO (SE) | 1984-12-12 | — | — | EP | disclosed |