SCHEMBL10707604

SCHEMBL10707604

C=C(C(=O)O)C(C)(C)CC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10661684 0.80 KDM4E (0.33) KDM4ETSHRTDP1
SCHEMBL5147447 0.74 TET2 (0.34)
SCHEMBL11042864 0.72
SCHEMBL10952663 0.72 KDM4E (0.32) KDM4ETSHRTDP1
SCHEMBL6063482 0.72 KDM4E (0.41) KDM4ETSHRTDP1GAA
SCHEMBL1733784 0.72 TET2 (0.44) KDM4ETSHRTDP1
SCHEMBL3205701 0.71 TSHR (0.35) KDM4ETSHRTDP1
SCHEMBL24871279 0.69 CYP1A2 (0.33) KDM4ETSHRTDP1
SCHEMBL3775748 0.69 TET2 (0.37)
SCHEMBL1005511 0.69 TET2 (0.34) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0103761-B1 COPOLYMERS FOR OPTICAL FIBERS Daikin Kogyo Co., Ltd. (JP) 1988-05-18 EP disclosed