Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347810 | 0.75 | — | — | |
| SCHEMBL347809 | 0.75 | — | — | |
| SCHEMBL10709363 | 0.67 | TSHR (0.43) | TSHRTHRBBLMPMP22NPSR1 | |
| SCHEMBL348320 | 0.65 | — | — | |
| SCHEMBL348319 | 0.65 | — | — | |
| SCHEMBL9487219 | 0.63 | TSHR (0.39) | TSHRTHRBBLMPMP22NPSR1 | |
| SCHEMBL9911181 | 0.63 | — | — | |
| SCHEMBL10707763 | 0.63 | TSHR (0.39) | TSHRTHRBBLMPMP22NPSR1 | |
| SCHEMBL7089266 | 0.63 | — | — | |
| SCHEMBL7089268 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789736-A | DIAGNOSTIC RADIOPHARMACEUTICAL | AMERSHAM INTERNATIONAL PLC (GB) | 1988-12-06 | — | — | US | disclosed |
| EP-0194843-A2 | Complexes of technetium-99m with propylene amine oximes | AMERSHAM INTERNATIONAL plc (GB) | 1986-09-17 | — | — | EP | disclosed |