Prococene Ii

Prococene Ii

SCHEMBL1070896

CCOc1cc2c(cc1OC)C=CC(C)(C)O2.COc1cc2c(cc1OC)OC(C)(C)C=C2

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR3 O15455 1/20 0.53
HIF1A Q16665 2/20 0.49
EPAS1 Q99814 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119216 1.00 TLR3 (0.53) TLR3HIF1AEPAS1
SCHEMBL10510924 1.00 TLR3 (0.53) TLR3HIF1AEPAS1
SCHEMBL10742529 0.94 TLR3 (0.58) TLR3
Prococene Ii SCHEMBL119925 0.91 ODC1 (0.54) TLR3HIF1AEPAS1
Prococene Ii SCHEMBL1276532 0.90 TLR3 (0.48) TLR3HIF1AEPAS1
SCHEMBL10508060 0.88 TLR3 (0.51) TLR3HIF1AEPAS1
SCHEMBL10507493 0.87 TLR3 (0.50) TLR3HIF1AEPAS1
SCHEMBL10508738 0.86 TLR3 (0.49) TLR3HIF1AEPAS1
SCHEMBL10508118 0.85 TLR3 (0.48) TLR3HIF1AEPAS1
SCHEMBL546060 0.85 TLR3 (0.48) TLR3HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784039-A1 RHEOLOGICAL MODIFIERS FOR SPRAY DRIFT CONTROL IN AGROCHEMICAL EMULSIONS Rohm and Haas Company (US) 2021-03-03 EP disclosed
WO-2017205751-A1 IMPROVED INSECT CONTROL STRATEGIES UTILIZING PHEROMONES AND RNAI PROVIVI, INC. (US) 2017-11-30 WO disclosed
WO-2017112887-A1 METHOD FOR MANAGING RESISTANCE TO INSECTICIDAL TRAITS AND CHEMICALS USING PHEROMONES PROVIVI, INC. (US) 2017-06-29 WO disclosed
EP-2268138-A2 SILICON DIOXIDE DISPERSION Evonik Degussa GmbH (DE) 2011-01-05 EP disclosed
WO-2009095141-A2 SILICON DIOXIDE DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed