Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704062 | 0.89 | MEN1 (0.41) | MEN1KMT2ATRPA1LIMK1NPC1 | |
| SCHEMBL10703856 | 0.88 | NPC1 (0.43) | MEN1KMT2ALIMK1NPC1RAB9A | |
| SCHEMBL10714921 | 0.85 | CNR1 (0.41) | MEN1KMT2ANPC1RAB9AROCK2 | |
| SCHEMBL10704876 | 0.85 | MEN1 (0.43) | MEN1KMT2ATRPA1NPC1RAB9A | |
| SCHEMBL10703512 | 0.84 | MEN1 (0.44) | MEN1KMT2ALIMK1NPC1RAB9A | |
| SCHEMBL10707150 | 0.84 | GCGR (0.48) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL10493505 | 0.83 | MEN1 (0.44) | MEN1KMT2ALIMK1NPC1RAB9A | |
| SCHEMBL10706436 | 0.83 | HDAC6 (0.46) | MEN1KMT2ALIMK1NPC1RAB9A | |
| SCHEMBL10703872 | 0.82 | HDAC6 (0.43) | MEN1KMT2ALIMK1NPC1RAB9A | |
| SCHEMBL10710564 | 0.81 | NPC1 (0.42) | MEN1KMT2ATRPA1LIMK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0116729-A2 | Benzoylurea compounds and pesticidal compositions comprisingsame | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |