Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | POLB | P06746 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10990529 | 0.92 | KDM4E (0.42) | KDM4EPOLBMAPTL3MBTL1GAA | |
| SCHEMBL10990527 | 0.92 | KDM4E (0.42) | KDM4EPOLBMAPTL3MBTL1GAA | |
| SCHEMBL10680460 | 0.89 | MEN1 (0.38) | KDM4EPOLBMAPTGAAMEN1 | |
| SCHEMBL10680454 | 0.89 | MEN1 (0.38) | KDM4EPOLBMAPTGAAMEN1 | |
| SCHEMBL11444997 | 0.89 | MEN1 (0.38) | KDM4EPOLBMAPTGAAMEN1 | |
| SCHEMBL11453387 | 0.89 | MEN1 (0.38) | KDM4EPOLBMAPTGAAMEN1 | |
| SCHEMBL10679992 | 0.81 | MEN1 (0.38) | KDM4EPOLBMAPTL3MBTL1GAA | |
| SCHEMBL10679997 | 0.81 | MEN1 (0.38) | KDM4EPOLBMAPTL3MBTL1GAA | |
| SCHEMBL10676899 | 0.78 | MEN1 (0.37) | KDM4EPOLBL3MBTL1GAAMEN1 | |
| SCHEMBL10676907 | 0.78 | MEN1 (0.37) | KDM4EPOLBL3MBTL1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |