Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376154 | 0.83 | HIF1A (0.41) | HIF1AEPAS1TSHRTYMPEPHX1 | |
| SCHEMBL17008157 | 0.80 | TSHR (0.57) | HIF1ATSHRTYMPCYP19A1THRB | |
| SCHEMBL5679424 | 0.77 | TSHR (0.50) | HIF1ATSHRTYMPCYP19A1THRB | |
| SCHEMBL10490602 | 0.77 | TYMP (0.41) | HIF1AEPAS1TSHRTYMPEPHX1 | |
| SCHEMBL29286066 | 0.76 | IGF1R (0.47) | CYP19A1ALDH1A1TDP1 | |
| SCHEMBL28986195 | 0.75 | IGF1R (0.47) | HIF1AEPAS1CYP19A1ALDH1A1 | |
| SCHEMBL7084583 | 0.74 | HIF1A (0.41) | HIF1AEPAS1TSHRTYMPEPHX1 | |
| SCHEMBL6663031 | 0.74 | HIF1A (0.41) | HIF1AEPAS1TSHRTYMPEPHX1 | |
| SCHEMBL9810574 | 0.74 | HIF1A (0.49) | HIF1AEPAS1TSHRTRPV1THRB | |
| SCHEMBL28163085 | 0.74 | HIF1A (0.41) | HIF1AEPAS1TSHRTYMPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-S6261981-A | PORPHYRIN DERIVATIVE | MITSUBISHI CHEM IND LTD | 1987-03-18 | — | — | JP | disclosed |
| JP-62061981-A | — | — | 0001-01-01 | — | — | JP | disclosed |