⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266268 | 0.76 | NOTUM (0.33) | — | |
| SCHEMBL23234066 | 0.76 | — | — | |
| SCHEMBL22769438 | 0.68 | KMT2A (0.37) | — | |
| SCHEMBL17529626 | 0.65 | — | — | |
| SCHEMBL17841784 | 0.65 | — | — | |
| SCHEMBL81364 | 0.63 | — | — | |
| SCHEMBL260501 | 0.63 | — | — | |
| SCHEMBL16371861 | 0.63 | — | — | |
| SCHEMBL18641979 | 0.62 | — | — | |
| SCHEMBL750791 | 0.62 | CYP11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10207985-B2 | Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| EP-3033330-B1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-19 | — | — | EP | disclosed |
| CN-105452225-B | Cyclobutylmethyl amide compound as nematicide | 先正达参股股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-105431414-B | The 4 round rings formamides as nematicide | 先正达参股股份有限公司 | 2018-06-15 | — | — | CN | disclosed |
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-20160176806-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-23 | — | — | US | disclosed |
| EP-3033330-A2 | NOVEL COMPOUNDS | Syngenta Participations AG (CH) | 2016-06-22 | — | — | EP | disclosed |
| US-20160157485-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015040141-A1 | CYCLOBUTYLCARBOXAMIDES AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-26 | — | — | WO | disclosed |
| WO-2015022265-A2 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |
| EP-0230110-A1 | Pharmacologically active pyrrole and pyrazole derivatives | FISONS plc (GB) | 1987-07-29 | — | — | EP | disclosed |