SCHEMBL1071906

SCHEMBL1071906

[SiH3]C1(OCC2CO2)CCCCO1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28577846 0.80 TSHR (0.32) TSHRALDH1A1
SCHEMBL1812693 0.73
SCHEMBL28885792 0.73
SCHEMBL4254048 0.71 TSHR (0.33) TSHRMAPK1ALDH1A1TDP1
SCHEMBL1837501 0.70 MAPT (0.31)
SCHEMBL2170086 0.70
SCHEMBL8512777 0.70 TSHR (0.47) TSHRMAPK1ALDH1A1TDP1
SCHEMBL6384094 0.70 TSHR (0.40) TSHRMAPK1ALDH1A1TDP1
SCHEMBL18094446 0.70 TSHR (0.40) TSHRMAPK1ALDH1A1TDP1
SCHEMBL1244016 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3844218-A1 ELECTRICAL OPERATING MEANS HAVING AN INSULATION SYSTEM, AND METHOD FOR PRODUCING THE INSULATION SYSTEM Siemens Aktiengesellschaft (DE) 2021-07-07 EP claimed
CN-106967208-B Coated particles 味之素株式会社 2021-09-10 CN disclosed
CN-108355472-B Carbon dioxide absorbent of hydrophobic modified polyethyleneimine and application thereof 四川大学 2020-09-29 CN disclosed
US-10450407-B2 Coated particles AJINOMOTO CO., INC. (JP) 2019-10-22 US disclosed
US-20170137563-A1 COATED PARTICLES AJINOMOTO CO., INC. (JP) 2017-05-18 US disclosed
EP-1383817-B1 FURTHER REACTED HALOGEN OR EPOXY LINKER-ALKOXY COMPOUND PRODUCT AS SUFACTANT COGNIS IP MAN GMBH (DE) 2011-01-19 EP disclosed
EP-1383817-A4 FURTHER REACTED HALOGEN OR EPOXY LINKER-ALKOXY COMPOUND PRODUCT AS SUFACTANT COGNIS IP MAN GMBH (DE) 2006-12-06 EP disclosed
EP-1383817-A1 FURTHER REACTED HALOGEN OR EPOXY LINKER-ALKOXY COMPOUND PRODUCT AS SUFACTANT Cognis Corporation (US) 2004-01-28 EP disclosed
US-6576736-B2 Reaction product of a trihalo compound or epihalohydrin, a alkylene oxide adduct, and another reactant such as isocyanate, polysiloxane, acid, phosphate, sulfate, epoxy, acrylate, or methylolurea; antifoaming agents, surfactants COGNIS CORPORATION 2003-06-10 US disclosed
US-20020169258-A1 Compounds and compositions useful as surfactants and methods for their preparation COGNIS IP MANAGEMENT GMBH (DE) 2002-11-14 US disclosed
WO-2002081538-A1 FURTHER REACTED HALOGEN OR EPOXY LINKER-ALKOXY COMPOUND PRODUCT AS SUFACTANT COGNIS CORPORATION (US) 2002-10-17 WO disclosed