Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721439 | 0.87 | CYP3A4 (0.61) | CYP3A4CYP2C9ABCB1POLBHPGD | |
| SCHEMBL10721558 | 0.86 | ABCB1 (0.71) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL28340060 | 0.85 | ABCB1 (0.74) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL10719280 | 0.85 | CYP3A4 (0.76) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL10721860 | 0.82 | CYP3A4 (0.59) | CYP3A4CYP2C9ABCB1POLBHPGD | |
| SCHEMBL10718725 | 0.82 | POLB (0.73) | CYP3A4CYP2C9ABCB1POLBHPGD | |
| SCHEMBL15364049 | 0.81 | CYP3A4 (0.49) | CYP3A4CYP2C9ABCB1 | |
| SCHEMBL10719225 | 0.80 | ABCB1 (0.73) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL10719961 | 0.79 | HPGD (0.78) | CYP3A4CYP2C9ABCB1POLBHPGD | |
| SCHEMBL10719103 | 0.79 | CYP3A4 (0.52) | CYP3A4CYP2C9ABCB1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |