Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.74 |
| ▸ | MYLK | Q15746 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | GMNN | O75496 | 2/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 7/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207926 | 0.86 | KMT2A (0.76) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL13498156 | 0.85 | POLB (0.74) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL2869228 | 0.85 | CYP3A4 (1.00) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29370764 | 0.84 | MAPK1 (1.00) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1848494 | 0.84 | MAPK1 (1.00) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1986979 | 0.83 | CYP3A4 (0.95) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL31684036 | 0.83 | TSHR (1.00) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL493231 | 0.83 | TSHR (1.00) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL31684034 | 0.82 | TSHR (0.78) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL4555453 | 0.82 | TSHR (0.78) | SMN1; SMN2KMT2AMAPK1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62087581-A | — | — | None | — | — | JP | disclosed |
| JP-S6287581-A | NAPHTHALENESULFONAMIDE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1987-04-22 | — | — | JP | disclosed |