Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.33 |
| ▸ | S100A10 | P60903 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718703 | 1.00 | HRH3 (0.64) | HRH3ANXA2S100A10CRBNHTR2C | |
| SCHEMBL10719966 | 1.00 | HRH3 (0.64) | HRH3ANXA2S100A10CRBNHTR2C | |
| SCHEMBL4301727 | 0.87 | HRH3 (0.73) | HRH3 | |
| SCHEMBL4301730 | 0.87 | HRH3 (0.73) | HRH3 | |
| SCHEMBL7025858 | 0.87 | HRH3 (0.73) | HRH3 | |
| SCHEMBL4301735 | 0.87 | HRH3 (0.73) | HRH3 | |
| SCHEMBL13660563 | 0.81 | HRH3 (0.68) | HRH3 | |
| SCHEMBL4294096 | 0.81 | HRH3 (0.48) | HRH3 | |
| SCHEMBL13660566 | 0.81 | HRH3 (0.48) | HRH3 | |
| SCHEMBL10721503 | 0.79 | HRH3 (0.73) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241298-A2 | 3-diphenyl substituted octahydroindolizine analgesic compounds | McNeilab, Inc. (US) | 1987-10-14 | — | — | EP | disclosed |
| US-4683239-A | 3-diphenyl substituted octahydroindolizine analgesic compounds | MCNEILAB, INC. (US) | 1987-07-28 | — | — | US | disclosed |