Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403345 | 1.00 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10544966 | 1.00 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10403864 | 0.89 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10546566 | 0.85 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10546401 | 0.84 | GAA (0.34) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10546393 | 0.84 | GAA (0.34) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL13953294 | 0.83 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10544918 | 0.83 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL14849507 | 0.82 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL14866125 | 0.81 | GAA (0.47) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229369-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |