Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.41 |
| ▸ | GBA1 | P04062 | 9/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20854595 | 0.98 | MEN1 (0.57) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL29013371 | 0.93 | TSHR (0.56) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL27576535 | 0.89 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL18954725 | 0.89 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8478995 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8483594 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1115457 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL18954849 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8482624 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8611137 | 0.86 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275459-B1 | POLYFUNCTIONAL VINYL AROMATIC COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND RESIN COMPOSITION | NIPPON STEEL CHEMICAL CO (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-2275459-A1 | POLYFUNCTIONAL VINYL AROMATIC COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND RESIN COMPOSITION | Nippon Steel Chemical Co., Ltd. (JP) | 2011-01-19 | — | — | EP | disclosed |