Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722160 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10728312 | 0.98 | HDAC1 (0.97) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8355645 | 0.83 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL20910939 | 0.83 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL31297136 | 0.83 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10727767 | 0.83 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL20886119 | 0.83 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL1374669 | 0.82 | HDAC1 (0.67) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10722424 | 0.81 | HDAC1 (0.68) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL19789098 | 0.81 | HDAC1 (0.97) | HDAC1HDAC2HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670469-A | ANTIASTHMATIC AGENTS; CARDIOVASCULAR DISORDERS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1987-06-02 | — | — | US | disclosed |
| EP-0127726-A1 | Hydroxamic acids, their preparation and their use in pharmaceutical compositions | VEB Fahlberg-List Magdeburg (DD) | 1984-12-12 | — | — | EP | disclosed |