Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10459167 | 0.99 | MEN1 (0.66) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL10719616 | 0.90 | KCNH2 (0.58) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL16307518 | 0.90 | KCNH2 (0.72) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL10461861 | 0.89 | KCNH2 (0.70) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL10460508 | 0.86 | KCNH2 (0.64) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL10459137 | 0.84 | KCNH2 (0.59) | MEN1KMT2AKCNH2HRH3PAX8 | |
| Fumaric Acid SCHEMBL10555655 | 0.84 | KCNH2 (0.54) | MEN1KMT2AKCNH2PAX8 | |
| SCHEMBL9492355 | 0.84 | KCNH2 (0.49) | MEN1KMT2AKCNH2PAX8 | |
| SCHEMBL10459164 | 0.84 | KCNH2 (0.64) | MEN1KMT2AKCNH2HRH3PAX8 | |
| SCHEMBL10460419 | 0.84 | KCNH2 (0.64) | MEN1KMT2AKCNH2HRH3PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |