Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CASP1 | P29466 | 4/20 | 0.57 |
| ▸ | CASP7 | P55210 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188796 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL1679606 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL888478 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL15124782 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL8403748 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL165951 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL2778091 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL336407 | 1.00 | CA12 (0.67) | CA12CA9CA1CA2CA7 | |
| SCHEMBL4074640 | 0.99 | CA12 (0.65) | CA12CA9CA1CA2CA7 | |
| SCHEMBL7766916 | 0.99 | CA12 (0.65) | CA12CA9CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11602528-B2 | Method for the treatment of Pompe disease using 1-deoxynojirimycin derivatives | AMICUS THERAPEUTICS, INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-10144941-B2 | Method and compositions for improved lignocellulosic material hydrolysis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-12-04 | — | — | US | disclosed |
| US-20180221357-A1 | METHOD FOR THE TREATMENT OF POMPE DISEASE USING 1-DEOXYNOJIRIMYCIN DERIVATIVES | AMICUS THERAPEUTICS, INC. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20160051528-A1 | Method for the Treatment of Pompe Disease Using 1-Deoxynojirimycin Derivatives | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2016-02-25 | — | — | US | disclosed |
| US-20160032340-A1 | Method and Compositions for Improved Lignocellulosic Material Hydrolysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-02-04 | — | — | US | disclosed |
| US-9181184-B2 | Method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives | AMICUS THERAPEUTICS, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-8586828-B2 | Polypeptides having beta-glucosidase activity and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2013-11-19 | — | — | US | disclosed |
| US-20130189744-A1 | Method and Compositions for Improved Lignocellulosic Material Hydrolysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-07-25 | — | — | US | disclosed |
| US-20110131686-A1 | Polypeptides having beta-glucosidase activity and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2011-06-02 | — | — | US | disclosed |
| EP-2274432-A1 | A METHOD FOR THE PRODUCTION OF A HUMAN PROTEIN IN A PLANT, IN PARTICULAR A HUMAN RECOMBINANT LYSOSOMAL ENZYME IN A CEREAL ENDOSPERM | Transactiva SRL (IT) | 2011-01-19 | — | — | EP | disclosed |
| US-20060264467-A1 | Method for the treatment of Pompe disease using 1-deoxynojirimycin and derivatives | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2006-11-23 | — | — | US | disclosed |
| US-20060031965-A1 | In- seed expression of lysosomal enzymes | PLANTECHNO S.R.L. (IT) | 2006-02-09 | — | — | US | disclosed |
| EP-1480510-A2 | EXPRESSION OF LYSOSOMAL ENZYMES IN PLANT SEEDS | Plantechno SRL (IT) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003073839-A2 | EXPRESSION OF LYSOSOMAL ENZYMES IN PLANT SEEDS | PLANTECHNO S.R.L (IT) | 2003-09-12 | — | — | WO | disclosed |
| EP-0254771-B2 | Detection of microbes in a sample | EDBERG STEPHEN C (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0649471-A4 | RECOMBINANT CELLULASES. | COMMW SCIENT IND RES ORG (AU) | 1997-06-04 | — | — | EP | disclosed |
| EP-0649471-A1 | RECOMBINANT CELLULASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994000578-A1 | RECOMBINANT CELLULASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-01-06 | — | — | WO | disclosed |
| US-4925789-A | COLORIMETRIC ANALYSIS | EDBERG STEPHEN C (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0254771-A2 | Detection of microbes in a sample | Edberg, Stephen C. (US) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221357-A1 | METHOD FOR THE TREATMENT OF POMPE DISEASE USING 1-DEOXYNOJIRIMYCIN DERIVATIVES | GAA, MAN2B1, MAN1B1 | CA12 3900/4885CA9 2445/4885CA1 4556/4885 |
| US-20160051528-A1 | Method for the Treatment of Pompe Disease Using 1-Deoxynojirimycin Derivatives | GAA, MAN2B1, MAN1B1 | CA12 3975/4885CA9 2507/4885CA1 4562/4885 |
| US-20060264467-A1 | Method for the treatment of Pompe disease using 1-deoxynojirimycin and derivatives | GAA, MAN2B1, MAN1B1 | CA12 3854/4885CA9 2457/4885CA1 4518/4885 |
| US-11602528-B2 | Method for the treatment of Pompe disease using 1-deoxynojirimycin derivatives | GAA, MAN2B1, MAN1B1 | CA12 3900/4885CA9 2445/4885CA1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.