Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725323 | 1.00 | SPHK1 (0.49) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10725313 | 1.00 | SPHK1 (0.49) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10726156 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10726137 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10728226 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10726144 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10728219 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10728237 | 0.96 | TSHR (0.56) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10610776 | 0.96 | SPHK1 (0.50) | SPHK1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL10610767 | 0.96 | SPHK1 (0.50) | SPHK1TSHRHSD17B10MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144648-B1 | LIQUID CRYSTALS: DERIVATIVES OF CYCLOHEXYLBENZENE AND CYCLOHEXYLBIPHENYL | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-10-21 | — | — | EP | disclosed |
| US-4652089-A | PACKING FOR CHROMATOGRAPHY COLUMNS, ELECTRO-OPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0144648-A2 | Liquid crystals: derivatives of cyclohexylbenzene and cyclohexylbiphenyl | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-06-19 | — | — | EP | disclosed |