SCHEMBL10725367

SCHEMBL10725367

Oc1cc2ccccc2cc1-c1nc2ccccc2o1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.71
KDM6A O15550 1/20 0.71
MAPT P10636 10/20 0.62
ALDH1A1 P00352 8/20 0.62
KDM4E B2RXH2 8/20 0.62
HPGD P15428 7/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
HSD17B10 Q99714 5/20 0.62
TP53 P04637 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
PKM P14618 2/20 0.62
GLA P06280 1/20 0.62
GAA P10253 1/20 0.62
CASP1 P29466 1/20 0.62
CASP7 P55210 1/20 0.62
TOP2A P11388 1/20 0.59
PTGS2 P35354 1/20 0.57
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1296601 0.91 KDM6B (0.78) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL6628246 0.88 KDM6B (0.61) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL18065788 0.86 KDM6B (0.54) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL1550348 0.84 TOP2A (0.79) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL8373929 0.83 KDM6B (0.77) KDM6BKDM6AMAPTALDH1A1KDM4E
Anthracene SCHEMBL29003509 0.83 NPC1 (0.66) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL56592 0.82 TOP2A (0.82) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL29401377 0.82 TOP2A (0.82) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL17654013 0.81 KDM6B (0.79) KDM6BKDM6AMAPTALDH1A1KDM4E
SCHEMBL30900831 0.81 KDM6B (0.79) KDM6BKDM6AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9466804-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2016-10-11 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150357587-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150333279-A1 ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-19 US disclosed
US-7642358-B2 Substituted phenylacetic acids METABOLEX, INC. (US) 2010-01-05 US disclosed
US-7642358-B2 Substituted phenylacetic acids METABOLEX, INC. (US) 2010-01-05 US disclosed
US-4687721-A FORMED FROM A COUPLER AND DIAZONIUM SALT TOGETHER WITH DISAZO COMPOUND MITSUBISHI PAPER MILLS, LTD. (JP) 1987-08-18 US disclosed
US-4206144-A N,N-Dialkyl-N-aminoalkyl-N-(amino or nitro)phenylalkyl- and N-methyl-N-[3-(amino or nitro)phenoxy-2-hydroxy-1-propyl]-N,N-bis(3-aminopropyl)quaternary ammonium salts STERLING DRUG INC. (US) 1980-06-03 US disclosed
US-4146558-A Azo dyestuff intermediate nitro- or aminobenzenes ring-substituted by a quaternized amine alkyl or amino-alkoxy group STERLING DRUG INC. (US) 1979-03-27 US disclosed
US-4103092-A Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1978-07-25 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed