Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729567 | 0.93 | POLB (0.48) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10724408 | 0.92 | POLB (0.50) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10725112 | 0.91 | POLB (0.52) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10724644 | 0.91 | POLB (0.52) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10730500 | 0.91 | POLB (0.52) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10725085 | 0.91 | POLB (0.52) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10724414 | 0.88 | POLB (0.40) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10730533 | 0.77 | POLB (0.43) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10729449 | 0.76 | POLB (0.41) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL10991341 | 0.76 | EGLN3 (0.56) | POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643998-A | Imidazolylalkylthienyl tetrahydropyridazines and processes for their use | A. NATTERMAN & CIE GMBH (DE) | 1987-02-17 | — | — | US | disclosed |