Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730405 | 0.95 | ACE (0.59) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10730286 | 0.94 | ACE (0.58) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10724415 | 0.86 | ACE (0.57) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10726884 | 0.85 | ACE (0.56) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10724212 | 0.84 | ACE (0.57) | ACE | |
| SCHEMBL19645413 | 0.83 | ACE (0.69) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4671537 | 0.81 | ACE (0.61) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4671532 | 0.81 | ACE (0.61) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1221172 | 0.80 | ACE (0.60) | ACELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4669890 | 0.80 | ACE (0.60) | ACELMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634716-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1987-01-06 | — | — | US | disclosed |