Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743168 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL11745435 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL11740658 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL9345659 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL17629047 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL11749087 | 1.00 | MAPT (0.57) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL14654918 | 0.98 | MAPT (0.54) | MAPTKMT2ATSHRFAAHCES2 | |
| SCHEMBL25340115 | 0.92 | TSHR (0.67) | MAPTKMT2ATSHRFAAHTERT | |
| SCHEMBL9513739 | 0.92 | TSHR (0.67) | MAPTKMT2ATSHRFAAHTERT | |
| SCHEMBL9015415 | 0.92 | TSHR (0.67) | MAPTKMT2ATSHRFAAHTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4676834-A | Novel compositions prepared from methyl substituted nitrogen-containing aromatic heterocyclic compounds and an aldehyde or ketone | THE DOW CHEMICAL COMPANY (US) | 1987-06-30 | — | — | US | disclosed |