Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 12/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462293 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP3A4SMN1; SMN2 | |
| SCHEMBL10736785 | 0.85 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10736133 | 0.85 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10739633 | 0.83 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10733563 | 0.80 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10733551 | 0.80 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10740169 | 0.79 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP3A4SMN1; SMN2 | |
| SCHEMBL6552175 | 0.78 | SLC6A4 (0.86) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6552048 | 0.78 | SLC6A4 (0.86) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6552194 | 0.78 | SLC6A4 (0.86) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705807-A | NERVOUS SYSTEM DISORDERS | LILLY INDUSTRIES LIMITED (GB) | 1987-11-10 | — | — | US | disclosed |
| EP-0008163-B1 | A PROCESS FOR PREPARING CIS-2-ARYL-3-AMINOMETHYL-BICYCLO (2,2,2) OCTANES AND THE COMPOUNDS 2-ARYL-3-AMINOMETHYLIDENE-BICYCLO (2,2,2) OCTANES | Lilly Industries Limited (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4215074-A | Process for preparing cis-bicyclooctylamines | LILLY INDUSTRIES LIMITED (GB) | 1980-07-29 | — | — | US | disclosed |
| EP-0008163-A1 | A process for preparing cis-2-aryl-3-aminomethyl-bicyclo (2,2,2) octanes and the compounds 2-aryl-3-aminomethylidene-bicyclo (2,2,2) octanes | Lilly Industries Limited (GB) | 1980-02-20 | — | — | EP | disclosed |