SCHEMBL1073504

SCHEMBL1073504

N#Cc1cccn1CCC(NS(=O)(=O)c1cccc2[nH]ccc12)C(=O)N1CCCN(C(=O)O)CC1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR10 P46092 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1313835 0.94 CCR10 (1.00) CCR10
SCHEMBL1310789 0.94 CCR10 (1.00) CCR10
SCHEMBL1074716 0.93 CCR10 (0.87) CCR10
SCHEMBL1310978 0.93 CCR10 (0.87) CCR10
SCHEMBL1075421 0.93 CCR10 (0.87) CCR10
SCHEMBL1311594 0.92 CCR10 (0.85) CCR10
SCHEMBL1311199 0.92 CCR10 (0.84) CCR10
SCHEMBL1311302 0.92 CCR10 (0.84) CCR10
SCHEMBL1313952 0.91 CCR10 (0.86) CCR10
SCHEMBL1075592 0.91 CCR10 (0.85) CCR10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276731-A1 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 Boehringer Ingelheim International GmbH (DE) 2011-01-26 EP disclosed
WO-2009126675-A1 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-10-15 WO disclosed