⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611107 | 0.67 | — | — | |
| SCHEMBL6292179 | 0.67 | — | — | |
| SCHEMBL6900802 | 0.63 | ELANE (0.33) | — | |
| SCHEMBL10360854 | 0.62 | — | — | |
| SCHEMBL14000768 | 0.62 | — | — | |
| SCHEMBL4352728 | 0.62 | — | — | |
| SCHEMBL7459363 | 0.62 | — | — | |
| SCHEMBL9321930 | 0.62 | — | — | |
| SCHEMBL2185838 | 0.59 | — | — | |
| SCHEMBL2765586 | 0.58 | ELANE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181217-B | Pyrazolo [1,5-a ] [1,3,5] triazine derivative and salt thereof and application of derivative and salt thereof in preparation of anti-cancer drugs | 陕西师范大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-114181217-A | Pyrazolo [1,5-a ] [1,3,5] triazine derivative and salt thereof and application of derivative and salt thereof in preparation of anti-cancer drugs | 陕西师范大学 | 2022-03-15 | — | — | CN | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| EP-2271645-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126514-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |
| EP-0122978-A1 | Therapeutically active di-, tri-, tetra- and penta-aza indenes | BIOMEASURE, INC. (US) | 1984-10-31 | — | — | EP | disclosed |