Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.76 |
| ▸ | HTR2C | P28335 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | PPARG | P37231 | 2/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737115 | 1.00 | NR1I2 (0.76) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11053023 | 1.00 | NR1I2 (0.76) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9679491 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5439979 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL8628827 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL8631702 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11055144 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10847228 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5439983 | 0.94 | NR1I2 (0.77) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10694596 | 0.93 | NR1I2 (0.65) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716158-A | CEPHALOSPORINS SUITABLE FOR ORAL ADMINISTRATION | SANKYO COMPANY LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| US-4707486-A | Diaryl piperidine containing esters of 1,4-dihydropyridines and coronary therapeutic use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-11-17 | — | — | US | disclosed |
| EP-0049118-B1 | CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4486425-A | ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |