Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388230 | 0.98 | MEN1 (0.33) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL4504832 | 0.98 | MEN1 (0.33) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL4509914 | 0.98 | MEN1 (0.33) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL11486391 | 0.88 | MAPT (0.38) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL14445407 | 0.86 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9673213 | 0.85 | TSHR (0.39) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL10681228 | 0.85 | TSHR (0.39) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL28884862 | 0.81 | MEN1 (0.35) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL3295702 | 0.80 | TSHR (0.39) | MAPTRAB9ANPSR1 | |
| SCHEMBL10988998 | 0.78 | NPSR1 (0.36) | MAPTRAB9ANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4681891-A | Dihydro-2,6-dimethyl pyridines, formulations and method of use for treating angina pectoris, high blood pressure or disturbances of cerebral or peripheral blood flow | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |