Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10738176 | 0.80 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| Oxalic Acid SCHEMBL10566788 | 0.80 | KMT2A (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10737106 | 0.79 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL12619921 | 0.75 | KMT2A (0.68) | MEN1KMT2AALDH1A1GAACA1 | |
| SCHEMBL10650928 | 0.74 | KMT2A (0.51) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10650939 | 0.74 | KMT2A (0.51) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL12188688 | 0.73 | KMT2A (0.66) | MEN1KMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL10566821 | 0.72 | KMT2A (0.45) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL9811297 | 0.71 | KMT2A (0.47) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL10651980 | 0.71 | KMT2A (0.47) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647588-A | 2-(substituted sulfamyl)-6-nitrobenzoic acid amides and pharmaceutical compositions | MERCK & CO., INC. (US) | 1987-03-03 | — | — | US | disclosed |