Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.76 |
| ▸ | HTR2C | P28335 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | FAP | Q12884 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.69 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.69 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | APEX1 | P27695 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740265 | 1.00 | PTGS1 (0.83) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10741947 | 0.94 | PTGS1 (0.81) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL7810054 | 0.94 | PTGS1 (0.81) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL7810048 | 0.94 | PTGS1 (0.81) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10741940 | 0.94 | PTGS1 (0.81) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL9683679 | 0.94 | PTGS1 (0.81) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10741863 | 0.94 | PTGS1 (0.73) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10741869 | 0.94 | PTGS1 (0.73) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10911610 | 0.94 | PTGS1 (0.73) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL10911611 | 0.94 | PTGS1 (0.73) | PTGS1NR1I2HTR2CMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716158-A | CEPHALOSPORINS SUITABLE FOR ORAL ADMINISTRATION | SANKYO COMPANY LIMITED (JP) | 1987-12-29 | — | — | US | claimed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | claimed |
| JP-57062287-A | — | — | None | — | — | JP | disclosed |
| JP-60034976-A | — | — | None | — | — | JP | disclosed |
| US-4716158-A | CEPHALOSPORINS SUITABLE FOR ORAL ADMINISTRATION | SANKYO COMPANY LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0049118-B1 | CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| JP-S6034976-A | CEPHALOSPORIN COMPOUND FOR ORAL ADMINISTRATION | SANKYO CO LTD | 1985-02-22 | — | — | JP | disclosed |
| US-4486425-A | ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| JP-S5762287-A | CEPHALOSPORIN COMPOUND FOR ORAL ADMINISTRATION | SANKYO CO LTD | 1982-04-15 | — | — | JP | disclosed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |