Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | HPD | P32754 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 8/20 | 0.46 |
| ▸ | IDO1 | P14902 | 7/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742868 | 0.91 | PDE4D (0.76) | PDE4DHPDTDO2IDO1IDO2 | |
| SCHEMBL10739746 | 0.90 | PDE4D (0.77) | PDE4DHPDTDO2IDO2POLB | |
| SCHEMBL10709171 | 0.88 | PDE4D (0.74) | PDE4DHPDKDM4EALDH1A1HPGD | |
| SCHEMBL10711517 | 0.88 | PDE4D (0.74) | PDE4DHPDTDO2IDO1IDO2 | |
| Afloqualone SCHEMBL29540781 | 0.86 | PDE4D (1.00) | PDE4DHPDKDM4EALDH1A1HPGD | |
| Afloqualone SCHEMBL400184 | 0.86 | PDE4D (1.00) | PDE4DHPDKDM4EALDH1A1HPGD | |
| SCHEMBL10741892 | 0.86 | PDE4D (0.71) | PDE4DPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL10736404 | 0.83 | POLB (0.53) | PDE4DHPDPOLBKDM4EALDH1A1 | |
| SCHEMBL10735755 | 0.82 | PDE4D (0.83) | PDE4DKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10737618 | 0.81 | PDE4D (0.74) | PDE4DHPDTDO2IDO1IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4714702-A | CENTRAL MUSCLE RELAXANTS | TANABE SEIYAKU CO., LTD. (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0116268-A1 | Novel quinazolinone derivative, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1984-08-22 | — | — | EP | disclosed |