SCHEMBL10743569

SCHEMBL10743569

CC1(C)CON(Cc2ccc(NN)cc2Br)C1=O

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.40
MAP2K1 Q02750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10739108 0.99 BRD4 (0.40) BRD4MAP2K1
SCHEMBL10736786 0.85 BRD4 (0.52) BRD4MAP2K1
SCHEMBL10744822 0.85 MAP2K1 (0.42) BRD4MAP2K1
Hydrochloric Acid SCHEMBL10739773 0.84 BRD4 (0.51) BRD4MAP2K1
Hydrochloric Acid SCHEMBL10738175 0.84 MAP2K1 (0.41) BRD4MAP2K1
SCHEMBL10458950 0.84 BRD4 (0.42) BRD4MAP2K1
SCHEMBL10744356 0.83 BRD4 (0.45) BRD4MAP2K1
SCHEMBL10740161 0.83 BRD4 (0.38) BRD4MAP2K1
SCHEMBL25072255 0.82 BRD4 (0.43) BRD4MAP2K1
Hydrochloric Acid SCHEMBL10737963 0.82 BRD4 (0.44) BRD4MAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4692182-A Herbicidal isoxazolidinone derivatives FMC CORPORATION (US) 1987-09-08 US disclosed