Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652115 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9628940 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9628169 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL710489 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL38926 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL710157 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL709920 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL7241563 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL7649641 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL7652102 | 1.00 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675352-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| US-4587346-A | ALKYLATION WITH ALKENE AND ACID CATALYST | CIBA-GEIGY CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |